Biome Balance 25 combines Lactobacillus plantarum and Lactobacillus rhamnosus with the exceptionally well-researched strains of bacteria, Lactobacillus acidophilus and Bifidobacterium bifidum. Rhamonsus is supporting immunity by stimulating the gut lining to produce mucin. Mucin is a mucous coating that prevents toxins from reaching the bloody. Plantarium secrets lactolin and has demonstrated anti-microbial effects, research looking at cold and general immunity. so, if someone has been ill, possible multiple antibiotic use in one year this formula comes into its own.